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Diari Valencià

The Vicky Foods Women's Race in Gandia Supports Prion Disease Research

The seventeenth edition of the race will allocate funds raised to a study on the maternal transmission of these neurodegenerative pathologies.

Generic image of a running shoe on asphalt, with a blurred urban background.
IA

Generic image of a running shoe on asphalt, with a blurred urban background.

The XVII Vicky Foods Women's Race in Gandia, organized by the Club d'Atletisme Safor Teika, will dedicate registration fees to a crucial study on the maternal transmission of prion diseases, which are rare neurodegenerative pathologies.

The XVII Vicky Foods Women's Race in Gandia has announced that its social contribution this year will be entirely dedicated to research into prion diseases. This initiative, which has become a key event in the Safor region, seeks to fund a study that will delve into the mechanisms of maternal transmission of these neurodegenerative pathologies, with the aim of preventing their inheritance by offspring.
The study, promoted by the Spanish Foundation for Prion Diseases in collaboration with the University of Toronto, will focus on the particularity that carrier women transmit the mutation with a higher frequency than expected, affecting approximately two out of three pregnancies. The principal investigators, Joaquín Castilla and Hasier Eraña from the Cooperative Research Center in Biosciences (CIC bioGUNE), aim to understand the biological mechanisms behind this transmission and develop therapies that allow carrier women to have children free of the pathogenic gene.
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"These are very serious and rare neurological diseases that are inherited from parents to children. An alteration in a gene called PRNP causes a protein in the body to stop functioning correctly, leading to progressive brain damage with fatal consequences."

Spanish Foundation for Prion Diseases
The results of this research, which will include a preliminary phase with animals, will not only be published in scientific journals but will also be transformed into practical material for clinical use, such as guides and monographs for genetic consultations. This project will allow for updating population risk calculations and the disease burden in regions with a high prevalence of these genetic mutations, such as some areas of Spain and Italy, thereby optimizing preventive strategies and healthcare resources.
The Spanish Foundation for Prion Diseases, a non-profit organization, is dedicated to supporting and researching these rare, devastating, and fatal diseases that affect the brain and nervous system. Its work not only covers the national scope but also serves as an international reference. The race, which will take place on Sunday, April 26, starting on Avenida de Les Esclaves, keeps registrations open at a price of 12 euros, of which 2 euros are allocated to this solidarity cause.

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